Archives for category: Choices we make
https://www.snopes.com/fact-check/hepatitis-c-drug-prices/

https://www.azquotes.com/quote/1133913

Then, if ‘greed is THAT good’, why blame Big Pharma for ‘buying’ politicians in order to extract as much profit as possible from their work?

Specially when it does work as advertised?

We priced the product at exactly the same as the existing standard of care, which worked about 50% of the time, and are providing a benefit that, based on real world experience, works about 98% of the time. From our perspective, it was a very good value.

I think our failure, if I have to take a step backwards, we were unable to have a good enough conversation with the payers. Perhaps we were a little conservative about what we could have or should have said to them to allow them to prepare for the number of patients that came forward. Honestly, it was far more than we thought. We did not think the system could or would try to handle as many patients as it did. We essentially quadrupled the number of patients treated in a year. That surge really created a lot of pain.

Ooops… so it’s the ‘payers’ who are hurting, not the patients themselves…

Gilead’s CEO Admits To ‘Failures’ In Setting Price of $1,000-A-Pill Breakthrough

Hepatitis C Treatment Highlights Disparity in Worldwide Drug Prices

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“Tolerance without reasonable limits is like walking around with a “KICK ME” sign that you put on your own back.”

John Faithful Hamer

Well…

‘Tolerance’ is a two dimensional thing.
‘Intensity’ and ‘wideness’.
What I tolerate and how far I allow things to go before I react to them.

Indiscriminate and limitless tolerance is, indeed, incompatible with life as we know it.

Actually.
It would mean total surrender to the first ‘bidder’.

(Absolute) intolerance would mean ‘constant warfare’.
A.k.a. beating the crap out of anybody who even dares to look up.
…. Being (feeling) compelled to attempt to …

Your choice.

Our choice?

– History is the story of what we remember of what had happened, right? Based on our shared individual recollections, the ‘written sources’ we have at our disposal and our interpretation of any other material traces we might have found… and properly preserved…

– Yep!

– Then no history, no matter how diligent and well intended the historian, will ever be the actual representation of what had really happened, back then!

– Well, you seem to be quite familiar with Heidegger’s work.

– I can’t say that. Popper’s injunction that science is more about being prepared to acknowledge your ignorance than about really knowing is enough for me.

– Then we might be soon delivered from History, after all.
When enough people will share your attitude/paradigm – that no matter how hard we’ll ever try we’ll never know anything for sure… it will be impossible for any would be dictator to pretend they have the ‘right’ answer for any problem we might encounter.

The worst thing about your parents passing away is the fact that from that moment on, every time you’ll turn to anybody for help that somebody will first pass judgement on you.

And why are we still trying to solve this riddle?

‘Cause this is indeed a riddle…

Remember those metaphorical stories whose heroes end up having to find the answer to one in order to save themselves/the day?
Like Sophocles’ “What walks on four feet in the morning, two in the afternoon and three at night?”

A riddle, of course, being a question which cannot be answered until the individuals attempting to solve it stick their heads out of the box into which the riddle had been framed.

So. Individualism? Collectivism?

Having grown up under communist rule – supposedly the most collectivist social arrangement to date, I can testify that there is no such thing as collectivism without individualism nor individualism without collectivism.

Libertarians’ mantra is that socialism/communism – and even liberalism, as Americans understand it, is a form of collectivism. And, of course, that collectivism is bad for you.
Socialists, on the other hand, maintain that the current situation – which is seen as being bad, is the consequence of the growingly extreme individualism which plagues modern societies.

Interestingly enough, both sides are simultaneously right.
Communism is indeed bad for you and the bad aspects of today’s society are a consequence of callous selfishness.

On the other hand, all communist societies are composed of a huge mass of obedient subjects AND a small number of individual, and very individualistic, leaders.
Similarly, all developed capitalist societies – including those sporting huge discrepancies between the shrinking number of haves and the growing number of utterly destitutes, have reached the current level of sophistication because most of their members continue to share the belief that ‘all men have been created equal and that all of them have certain, nonnegotiable, rights: Life, Liberty and the Pursuit of Happiness’.

“Share the belief…”
But wasn’t this the very definition of collectivism?
A social arrangement where the most important possession belongs to THE public?
Was there anything more consequential for what is currently known as the ‘Euro-Atlantic’ civilization than this shared belief? Other peoples have been in possession of way more abundant natural resources. Had reached ‘astronomical’ levels of civilization way before we were even able to wipe our noses… And yet…

Haven’t we, individual thinkers, figured out yet that unless we agree on ‘the basics’, we’ll be easy prey for the callous ‘snake oil merchantmen’ who have no qualms to use collectivist slogans to pitch some of us against the others?

Haven’t we figured out, yet, that there is no ‘political collectivism’ without fear? All collectivist social arrangements, both socialist and fascist/nazist, have been built using fear/contempt (of the other) to cement ‘the people’ into believing the lies proffered by false prophets. Lenin, Mussolini, Stalin, Hitler, Mao… Lies proffered by callously individualistic political agents… bent on satisfying their own domineering instincts and making ‘good use’ of pre-existing conditions.

Haven’t we figured out yet that individualism, the tame version developed along with the good aspects of the Western Civilization, is, by nature, the very beneficial consequence of the mutual respect which (still) exists among the members of our societies?

So, to answer the riddle, we need to understand that there is no real conflict between bona fide individualism and bona fide collectivism.
Just as there is no conflict between two perpendicular lines.

Since, by trade, I’m a mechanical engineer, I’ll use a very practical metaphor to illustrate this idea.
Consider a pressurized Oxygen tank. The more pressure inside, the more Oxygen you can store in it. The more useful the tank. Only if you ramp up the pressure too much, you end up with an explosion.
In this situation, you might consider ‘pressure’ to be in conflict with the ‘walls of the tank’, right?
Wrong. The conflict is only in your mind. Pressure is simply perpendicular to those walls. The more pressure those walls can withstand, the more useful that tank is for you.

But it’s your responsibility to determine the thickness and resilience of those walls. It’s your responsibility to choose how much to ramp up the pressure.
For the very simple reason that that tank is yours.
It is you who will suffer the consequences.


There is a technical reason. And some subjective ones. Acting in a synergic manner.

Trump had bean the darling of the high ratings/low expectations media for most of his adult life. During this period he had learned how to use it towards his own goal – an ever increasing notoriety, and those involved in the media had learned to love him back for the amount of publicity they had been able to sell on his back.

Now for the subjective ones.
First of all, he is a very ‘penetrant’ person. Like him or not, but you can’t ignore him.
Secondly, he happens to be the most powerful individual on Earth. Simply because he had been elected the President of the United States of America. Which is not only the most potent/civilized/democratic/you name it country, but also the leader of the free world. Meaning that the rest of the planet, democratic or not, sets it’s time after America’s clock. Willingly or unwillingly.
So the rest of world is watching anxiously everything that is going on in Washington. Wondering whether ‘Trump-ism’ will spread around. Or will remain yet another measure of American exceptionalism.

Thirdly, but maybe the most important reason, Trump can be analyzed as a symptom rather than as a cause.
In fact, there are a lot of Trumps scattered around the world.
Basically, there is very little difference between Trump and Putin. Trump and Erdogan. Trump and Bolsonaro. Trump and Dragnea – the most powerful politician in today’s Romania, my country. Even between Trump and Modi. Only none of these countries is similar to the US of A. None of them has such a distinguished democratic tradition.
And this is why so many people try to understand what’s going on.
Is Trump nothing more than an unhappy accident? Or the visible symptom of democracy becoming decrepit?

PS.
Even Abe is showing signs of contagion.
Post WWII Japan had survived by feeding whales to its people.
Now it is going to resume commercial whaling. In spite of all other previously whaling nations asking him to reconsider.
Really Abe? You need whale meat to survive?

“One of Pareto’s most noteworthy and controversial theories is that human beings are not, for the most part, motivated by logic and reason but rather by sentiment.”

Coming from an engineer – Pareto had started as one, this concept becomes even more noteworthy.
Why would a ‘professional using precision measurements and seeking consistently reproducible results’ focus his attention on sentiment rather than reason?

Because this is the reasonable thing to to?

And one of the reasons for which I tend to agree with him – besides being an engineer myself, is that he had started his studies using the most ‘reasonable’ instrument ever devised by man: “Residing in Florence, he studied philosophy and politics and wrote many periodical articles in which he first analyzed economic problems with mathematical tools.”

So, Pareto had reached the conclusion that human beings are driven mostly by sentiment after rationally analyzing the economic (and political) life.

OK. But what lies behind ‘sentiment’?

Pareto had proposed ‘residues’ as ‘motivation’ for sentiment. His theory is interesting only rather complicated. Almost byzantine. A well written summary can be read here.

What I find fascinating about Pareto’s theory is the rather veiled but certain correspondence which exists between his ‘residues’ and Maslow’s “hierarchy of needs”.

I’ll try to ‘raise the veil’ at a later date, today I’ll just point you towards a very relevant ‘coincidence’.

The psychologist had traveled the same road as the engineer.

Maslow (1943) initially stated that individuals must satisfy lower level deficit needs before progressing on to meet higher level growth needs. However, he later clarified that satisfaction of a needs is not an “all-or-none” phenomenon, admitting that his earlier statements may have given “the false impression that a need must be satisfied 100 percent before the next need emerges” (1987, p. 69).

Both had started ‘deterministically’, trying evidentiate ‘the’ (ironclad?) link between behavior and conditions – and expecting that link to be of a rational nature, only to reach the conclusion that individual sentiment/evaluation is at least as important – if not more so, as reason in the decision process. In shaping human behavior.


Democracy works. Authoritarianism works too.

Athens, the Ancient version, had become the dominant power of the Ancient Greece as a democracy. Only the Parthenon was build under Pericle’s rule. And Pericle was, for all intents and purposes, a dictator.
Rome, the Ancient version, had build a huge empire. As a democracy. Then enlarged it some more. As a growingly authoritarian and eventually discretionary regime.

England had started as the most democratic kingdom in Europe. Building upon the democratic traditions developed by the Vikings, the barons had forced King John to sign Magna Charta Libertatum. Way back in 1215.
Meanwhile, France – England’s neighbor and long time competitor, had become the dominant power in Medieval Europe. As an increasingly absolutist monarchy.

At some point, the people living in the future United States of America had decided that they had enough. That they wanted to enjoy the same privilege as their British counterparts. “No taxation without representation”.  George III would have no such a thing so the US had been established as the first democratic modern state. And the most successful to date. By almost every measure.
Following on America’s foot steps, the French had their Revolution. After a very short – and very tumultuous, democratic stint, they had reverted to authoritarianism. And conquered almost all Europe, under the command of Napoleon Bonaparte the First. Only to be eventually defeated by a coalition led by the more democratic British empire.

On the other side of Eur-Asia, things had been more linear.

The Russian Empire was developed in fits and starts. When the dictating ruler knew what he was doing – Peter the Great, for instance, things went forward. When not…
India had been, for all but the last 70 years or so, a melting pot of feuding dictatorships. Yet had developed a fascinating culture and much of what we currently call science and technology. The numbers our computers crunch had been invented there. And the steel we use to build our cars
The Chinese Middle Kingdom had once been the most civilized country on Earth. Then had crumbled under the assault of the marauding already democratic Europeans… only to revive, like the famous Phoenix… and all these while remaining submissive to a succession of authoritarian regimes.
Japan is a story by herself. Never fully authoritarian and yet still ‘imperative’ in many ways even today, she had somehow managed to put up a relatively good show. But for the period when she had succumbed to the ‘charms’ of hard core dictatorship, of course.

Coming back to Europe, I have to note that in the last century the inevitable tension between democracy and authoritarianism has produced immense tragedy.
WWI was the consequence of the inflexibility inherent to the authoritarian regimes. The leaders of the Keiserlich und Koniglich Habsburgic Empire, the Deutches Reich and the Russian Empire were not able to solve their disputes otherwise than dragging the whole continent into a huge mess.
Which, unsolved, had given birth to a second, and more horrible, one.
To complicate things even more, the battle was not fraught between the democratic regimes and the authoritarians.

An old Romanian saying posits that when God wants to punish someone, He starts by dulling their wits.

What if ‘fake news’ are a symptom of (some of the) journalists having earned the wrath of God?
Or is it the whole countries whom God wants to teach a lesson? Or two?


https://www.independent.co.uk/news/world/europe/vladimir-putin-says-he-has-never-made-a-mistake-because-god-wanted-him-to-be-perfect-10309628.html

What we currently call ‘science’ is both an activity and an attitude. Something some of us do and the way in which some of us see the world.

In current lingo, those who ‘do science’ are involved in ‘technology’ while those who see the world ‘scientifically’ partake in a certain philosophical tradition.
If we look at things in this way, it becomes obvious that doing science and thinking scientifically might not be the same thing.

Science, as an attitude, had sprung up in Ancient Greece, been kept alive by the early Islamic scholars, rekindled by the Medieval Catholic theologians, come of age during the Renaissance and ‘exploded’ after the Enlightenment.
Technology, on the other hand, is way older. And had been developed mainly elsewhere than the scientific attitude. China and India had been technological powerhouses and thriving civilizations in times when Europe was still learning to wash its hands before dinner.

‘Modern’ science – what we have now, appeared only after technological prowess had been married to the right attitude. 

OK.
It is easy to accept that technology, the more widely distributed part of ‘science’, had appeared as a consequence of mere necessity. People needed things in order to survive, then wanted things in order to increase their comfort… things which had to be produced… as efficiently as possible… hence people had put their minds to it and … voila!
But what had driven some of those around the Mediterranean Sea to develop the scientific attitude?

The same thing which drives us?
The attempt to find out the future, one second earlier than it really happens?
Because they thought, like we do, that reality is unique and that man is meant to master it?

Man, the guy who was made by God in His own image and who was told to rule the world?

Roger Bacon, Duns Scotus, Occam,  Galileo, Newton, Darwin, Georges Lemaitre… some of them might have been persecuted by the church – personally or had their their ideas ‘challenged’, but they all had been raised in the Christian tradition and had been active members of their religious communities. Even Galileo, the only one among these who had been ‘physically’ affected by the way in which his ideas had been received by his contemporaries, had a more or less ‘functional’ relationship with the heads of the Church… he had died in his own bed, arrested in his own villa, not at the stake …



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